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Yes, but it requires careful planning

These pathogenic bacteria can colonize the gut by exploiting epithelial damage and activate TH1/TH17 immune responses through virulence factors, such as the type III secretion system (108)

Thus, the healing of the esophagocutaneous, 82 gastrocutaneous, 83 duodenocutaneous, 84 colocutaneous, 85 vesicovaginalis, 86 and rectovaginalis fistulas, 87 assessed grossly, biomechanically and microscopically means demonstration of the both external and internal fistulas healing 82 - 87 and consequently, the realization of the simultaneous healing of different tissues

Vogl T, Glieder A (2013) Regulation of Pichia pastoris promoters and its consequences for protein production