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Huber-Lang, Markus
Undeniably powerful weight loss in a pen and a pill 1-3 Along with diet and exercise Wegovy HD In adults with obesity, Efficacy estimand: ~21% (20.7%) mean weight loss with Wegovy HD (semaglutide) injection 7.2 mg vs 2.4% with placebo at 72 weeks, in an idealized scenario estimating efficacy if all patients remained on treatment and used no other weight-loss therapies* Treatment regimen estimand: ~19% (18.8%) mean weight loss with Wegovy HD vs 3.9% with placebo at 72 weeks, for all patients in the trial regardless of whether patients stayed on treatment or took other weight-loss therapies For adults taking Wegovy for weight reduction: Those who tolerate the 2.4 mg dosage for at least 4 weeks and additional weight reduction is clinically indicated, the dosage may be increased to a maximum dosage of 7.2 mg subcutaneously once weekly
Limitations and Future Directions While the current study focused on a well-characterized group of young males with ASD and gathered standardized data from multiple sources, there are important limitations to consider
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