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4 Future challenges 4.1 Mechanistic validation across ocular pathologies Despite progress in understanding molecular pathways such as calcium channel modulation and mitochondrial mitophagy, the relative contributions of these mechanisms to specific diseases remain unclear

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Controlled early trials defined doses and common AEs

Individuals who should avoid glutathione injections include pregnant or breastfeeding women, those with liver or kidney disease, patients with history of severe allergic reactions, and anyone with unrealistic expectations about dramatic or permanent results