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Similarly, corticosteroids should be used with great caution in patients with Strongyloides hyperinfection and dissemination with widespread larval migration, often accompanied by severe enterocolitis and potentially fatal Gram- sepsis

Thus, the ability of an individual to metabolize ethanol is dependent upon the capacity of hepatocytes to carry out either of these two shuttles, which in turn is affected by the rate of the TCA cycle in the mitochondria