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Semaglutide has been studied across the SUSTAIN and STEP trial programmes, establishing robust evidence in both type 2 diabetes and obesity without diabetes populations

Both probiotics and prebiotics have a variety of biological actions, including outcompeting pathogenic microorganisms in the digestive tract, inactivating harmful metabolites, producing powerful bioactive molecules (short-chain fatty acids), modulating immune and metabolic signaling, improving overall digestive tract function, and enhancing central nervous system effects through the gutbrain axis

Please refer to the full 2020 ADA Standards of Care for additional details and recommendations regarding intensification of therapy beyond dual antihyperglycemic therapy

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