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This practice can be dangerous and is not recommended

However, up to 10% undergoes bioactivation to N -acetyl p -benzoquinone imine (NAPQI), a highly reactive electrophile, which is known to covalently bind to nucleophilic centers, including cysteine thiols in liver proteins (see Figure 1) (Jollow et al., 2015)

It is important to be cautious and seek medical advice when necessary to ensure the safety of using these substances together, especially for individuals who regularly consume alcohol or those with pre-existing liver conditions

The drug, Ojemda, is also the only systemic treatment option for pLGG that allows for a once-weekly treatment schedule, according to the company