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TRPV1 has been shown to be expressed in the brain, -cells (371), nociceptor C fibers, dorsal root ganglia, hepatocytes, spermatozoa (372), airway neurons (373), bladder and urothelium (374), blood vessels, and the whole gastrointestinal myenteric plexus (375), especially in colonic and rectal neurons (376)

This is an important distinction that suggests ipamorelin poses less desensitization risk than direct hormone supplementation

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The patient showed no recurrence 3 months following resection and is currently back to work, on pain medications, with complete resolution of her preoperative pain