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Figure 7, taken from an in vitro and ex vivo study assessing synbiotic combinations, shows for example significant differences in the abundance of specific bacterial groups such as Bifidobacteria and Lactobacilli in response to synbiotic treatments compared with probiotics or prebiotics alone [130]

Following renal injury, fibroblasts undergo differentiation into myofibroblasts, marked by the expression of alpha-smooth muscle actin and the development of excessive extracellular matrix proteins

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After OS production, aromatase activity is enhanced, which leads to higher E2 production