glp 1 effects on brain Mechanisms of glucagon-like-peptide in the beyond metabolic Glp-1 drugs offer brain benefits

In cell culture, tissue was treated with: a) GHK-Cu preparation and exposed to UV light (Tissue-PC), b) UV light exposure (Tissue-NC), and c) Negative control (without GHK-Cu preparation and light exposure)

Furthermore, 2-DG-mediated inhibition of glycolysis effectively reverses various electrophysiological alterations induced by epilepsy, suggesting that targeting lactate metabolism pathways could be a promising approach for the development of novel antiepileptic drugs [195] (Supplemental Table 2)

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Arbutin w/o/w nanoemulsions that were co-encapsulated with coumaric acid showed enhanced encapsulation efficiency, increased drug stability, sustained drug release, and improved skin delivery in comparison to the free drug (Wen et al., 2006a