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Such ratio significantly increased from baseline after 26 weeks of treatment with liraglutide 1.8 mg/day, indicating a reduction in liver steatosis, whereas it was unchanged in patients treated with lower doses of liraglutide, glimepiride or placebo

[99] showed different results using a retrospective matched cohort study that utilized the TriNetX, found no increased risk of NAION or ischemic optic neuropathy among patients with T2DM or elevated BMI prescribed semaglutide over 5 years