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Including milk thistle supplements can support detoxification processes and antioxidant defenses

Pediatr Blood Cancer 2007

CREB binds cAMP response elements (CRE) in genomic DNA causing the transcription of various genes including those encoding for steroidogenic enzymes (e.g., aromatase) and cholesterol transport, the precursor substrate for sex steroid synthesis (e.g., steroidogenic acute regulatory protein, StAR)