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melanocytes from the control skin and perilesional area of stable vitiligo lesions showed long, thin dendrites with a moderate number of melanosomes, in contrast to the melanocyte dendrites from the perilesional area of active vitiligo: retractable with few melanosomes.39 Langerhans cells are increased in the epidermis, the basement membrane is thickened, and degenerative alterations (e.g., cytoplasmic vacuolization) in basal melanocytes and keratinocytes are evidenced during disease activity

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Endothelial to mesenchymal transition in cardiovascular disease: JACC state-of-the-art review