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Correlation of a common mutation in the methylenetetrahydrofolate reductase gene with plasma homocysteine in patients with premature coronary artery disease

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Taken together, this also demonstrates that Fc-engineered human IgG variants with altered binding to FcRn behave differently in human and murine model systems, which highlights the importance of accounting for cross-species differences when studying Ab-based therapeutics and FcRn biology [101,102,103]

100300 mcg once daily, titrated upward gradually across an 812 week course (often dosed before bed, fasted)