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When B12 levels become problematic: High-dose supplementation (particularly doses exceeding 1,000 micrograms daily) Frequent B12 injections without medical supervision Underlying conditions affecting B12 metabolism Concurrent use of multiple B12-containing supplements The NHS does not set an upper safe limit for vitamin B12 because harmful effects from excessive intake have not been definitively established

Injection Technique General subcutaneous technique, following established clinical best-practice guidance [10] [11]

However, even if you eat enough to get the recommended dose (2.4 micrograms in people 14 and older), older adults and people with gastrointestinal issues may have problems absorbing it properly