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The findings highlight the nuanced ways incretin therapies act beyond pure metabolic regulation. Othmar Moser Researchers conducted a survey of 411 adults aged at least 18 years with obesity or overweight with at least one weight-related comorbidity who were receiving semaglutide or tirzepatide (median age, 39 years

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The key difference between a GLP-1 agonist and GLP-1 itself is that the drugs are modified to resist quick breakdown, so they last longer in the body than the natural hormone