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A combination of a hypocaloric diet (daily reduction by 500-1,000 kcal) and moderate-intensity exercise is likely to provide the best likelihood of sustaining weight loss over time

Addition of a large quantity of the enzyme would have increased the enzymatic contribution of the total rate of reaction mixture but that would have made the rate too fast to measure accurately and conveniently, especially at high MBB concentration

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Photosensitivity is also increased, making the use of sunscreen indispensable when venturing outdoors