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Enhanced drug delivery For combination therapy, microneedling creates temporary channels through the stratum corneum (skin barrier), allowing topical treatments to penetrate 510 deeper into the follicle than surface application

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In addition to its ability to sustain effective levels of adenosine triphosphate (ATP), nicotinamide adenine dinucleotide (NADH), and nicotinamide adenine dinucleotide phosphate (NADPH), and to maintain its ionic composition, it can also reduce methemoglobin and oxidized glutathione, synthesize new glutathione, and reseal its membrane if a portion of it is lost