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For weight loss, noticeable changes typically take longer, often becoming apparent between 8 to 12 weeks, depending on individual factors and adherence to the dosing schedule and lifestyle changes

2021 Aug 20;12(1):5064

For randomized controlled trials, the Cochrane RoB 2.0 tool was applied across seven domains: random-sequence generation, allocation concealment, blinding of participants and personnel, blinding of outcome assessment, incomplete outcome data, selective reporting, and other sources of bias

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