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Whether this translates to equivalent results depends on individual factors and goals

In particular, the prefrontal cortex (PFC), amygdala, and hippocampus are crucial for regulating emotion, stress responses, and motivation

Garcia-Echeverria et al (2004) presented a new compound (a pyrrolo[2,3-d] pyrimidine) that although inhibiting the IGF-1R and IR TK equipotently in cell-free systems, exhibited several-fold selectivity for the IGF-1R in a cellular context and reduced the growth of IGF-1R positive fibrosarcomas in vivo