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The gut microbiome may also adjust to new patterns of digestion and diet

PLoS ONE 8 , e61965 (2013)

In a statement, Wegovy's maker Novo Nordisk said it was "encouraged" by the new guidance from CMS but said it hopes to see Part D coverage expanded for "obesity medicines when used for chronic weight management." The drug maker is among those pushing for Congress to expand coverage of treatments for obesity

The addition of glucagon receptor activation creates additional metabolic effects that may modify the bloating experience, though detailed comparative data on specific symptoms like bloating is limited