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In rare cases, more serious concerns like pancreatitis or allergic reactions have been observed, though these events remain uncommon

However, others report minimal or no improvement, highlighting the varied effects of the drug on individuals

The FDA has announced a two-day public meeting of its Pharmacy Compounding Advisory Committee (PCAC) on July 2324, 2026, to formally evaluate whether seven bulk drug substances should be added to the Section 503A Bulk Drug Substances List (the 503A Bulks List)

Nat Rev Immunol 5:331342 Luo L, Schomaker S, Houle C, Aubrecht J, Colangelo JL (2014) Evaluation of serum bile acid profiles as biomarkers of liver injury in rodents