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Timed with Wellness Week, Barrymore opened up about training with Marnie Alton to drop the weight, not only for her role on the now-axed series Santa Clarita Diet, but for herself after giving birth to daughters Olive, now 7, and Frankie, now 4

This matters because GLP-1 and weed both affect appetite and reward pathways, just from opposite sides of the spectrum

In detail, the cellular landscape of AT shifts towards an increased abundance of AT macrophages (ATMs), which constitute the predominant immune cell type in obese WAT