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In aged skeletal muscle models, NNMT inhibitor treatment increased proliferating/active muscle stem cells by 60-75% following injury, myofiber cross-sectional area increased 1.8-fold at one week post-injury with high-dose treatment, and peak torque of injured muscle increased by 67% compared to control (p = 0.033), with no untoward systemic toxicity observed in plasma chemistry markers (Neelakantan et al., 2019)

Regenerating other antioxidants, such as vitamin C and E, making them more effective

Kim KA, Park PW, Kim HK, et al

The structural modifications used allow the simultaneous study of two incretin pathways within a single test molecule