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Description

Semaglutide can cause side effects, and they are not always mild

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The data: Most patients who got prescribed a GLP-1 for the first time in 2023 or 2024 ended up discontinuing treatment before long, and many never filled their prescription at all, according to a November 2025 IQVIA analysis of GLP-1 prescription claims

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Therefore, a dramatic decrease in plasma 5HT concentration after the SSRI treatment can be expected in these patients

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