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The most-cited animal work is a series of long-term experiments in CBA mice and Wistar rats reporting that pulsed administration of Epitalon increased mean and maximum lifespan, reduced the incidence of spontaneous tumour formation, and preserved oestrous cyclicity in females past the age at which controls became acyclic

Cytochrome P450-mediated alterations in clinical pharmacokinetic parameters of conventional drugs coadministered with piperine: a systematic review and meta-analysis

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