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Lower nocturnal melatonin levels and/or its urinary metabolite, 6-sulfatoxymelatonin, were found in migraine patients compared with healthy controls, and melatonin was shown to be more effective than placebo for the prevention of migraine in adults

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102 A review of the clinical evidence found melatonin therapy can improve sleep in individuals with tinnitus, but was unable to determine conclusively whether it can improve tinnitus