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Lactate promotes synthetic phenotype in vascular smooth muscle cells

Many labs specify a minimum purity threshold around 98%, and some suppliers such as Protide Health publish batch-specific HPLC data showing 99% purity or higher on their Certificates of Analysis

Altered gene expression of the astrocytic lactate efflux transporter (monocarboxylate transporter 4, SLC16A4) together with reduced lactate levels found in the spinal cord of hSOD1 G93A mice further suggest that metabolic interaction between neurons and astrocytes may be disrupted in ALS (Ferraiuolo et al., The potential of metabolic coupling between neurons and oligodendrocytes has gained a lot of interest in recent years and it appears that oligodendrocytes also can release lactate

After removing the needle, apply gentle pressure with a clean gauze pad for 10 secondsdo not rub the area, as rubbing increases bleeding and bruise formation