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doi: 10.1016/j.canep.2010.06.012

Therefore, Lf carries a huge potential as a main or secondary molecule to be used in brain-targeting delivery systems, either directly or indirectly (Huang et al., Several reviews explained that both microglia and astroglia contribute to PD by negatively affecting the balance of iron levels (Huang et al., 1-Methyl-4-phenylpyridinium (MPP + ) is a type of dopamine neurotoxin that induces Parkinson's disease and causes movement disorders (Tetrud and Langston, + , is selectively toxic to the substantia nigra and accumulates in the neurons (Langston et al., + cannot cross the bloodbrain barrier

Expert Opin Pharmacother (2012) 13(17):251131