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The role of barrier-respecting correction Effective cosmetic correction of a labial melanotic macule requires the same principles as the correction of broader lip hyperpigmentation: gentle exfoliation that respects the barrier, melanin synthesis inhibition at the enzymatic source, and barrier restoration to break the inflammatory cycle

(Source: Side Effects and Patient Safety Concerns GLP-1 analogues frequently cause gastrointestinal distress, nausea, and vomiting as side effects, which may deter long-term use

Tirzepatide, the active ingredient in Zepbound, is already approved in Lillys Mounjaro for T2D

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