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GSH is exclusively degraded at the extracellular level by cells expressing -glutamyltranspeptidase (GGT), such as those of the hepatobiliary tree and of other organs like the heart, kidney, lungs, pancreas, and seminal vesicles

For background on the GHRH pathway that CJC-1295 targets, Wikipedias growth hormone-releasing hormone overview provides foundational context

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These include allergic reactions ranging from mild skin reactions to potentially serious anaphylaxis (extremely rare), though true allergic reactions to glutathione itself are uncommon given its endogenous nature