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Disrupted glucose metabolism in ADRD is closely linked with an inflammatory and neurotoxic milieu, as increased presence of ROS and pro-inflammatory cytokines reduce expression of glucose transporters, disrupt insulin signalling, and reduce mitochondrial efficiency and function, resulting in impaired transport, uptake, and metabolism of glucose (RojasGutierrez et al., 2017
The dried WECP powder was reconstituted in desalinated water to obtain 1 mg/mL WECP aqueous solution
Melatonin prevents cisplatin-induced primordial follicle loss via suppression of PTEN/AKT/FOXO3a pathway activation in the mouse ovary
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