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Cell Host Microbe (2018) 24(1):5768 e3

This approach ensures that the nanomaterial will be activated primarily in the vicinity of pathogenic bacteria, which thrive in such environments and will remain inactive in the more neutral pH of healthy tissues, pH-responsive NPs are commonly made using materials like chitosan, which undergoes protonation in acidic conditions, leading to a release of encapsulated drugs or antimicrobial agents at infection sites

Well-positioned to test this further are current late-stage clinical trials of GLP-1 analogues, several of which are ongoing