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209211 One specific locus of interest is the GLP-1R, which plays a crucial role in insulin secretion and the regulation of glucose levels

It has several functions, including enhancing insulin secretion, reducing glucagon production, and slowing gastric emptying, which all synergistically work to reduce blood glucose levels

Taste disturbances are accompanied by other concerning symptoms such as persistent vomiting, severe abdominal pain, difficulty swallowing, or signs of dehydration

When used in combination with GLP-1, which has glucose-lowering action, it has been shown to be an effective treatment for T2DM and obesity