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An excess of estrogen, often referred to as estrogen dominance, can lead to hormonal imbalances and contribute to various health issues, including irregular periods, mood swings, and even certain cancers

It is unknown whether Zepbound causes thyroid C-cell tumors in humans

Then, in 2015, Lee and colleagues identified a previously overlooked open reading frame within the 12S ribosomal RNA gene of mtDNA and found that it encodes a functional peptide, MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) [1]

Larger-scale and longer-term clinical studies are needed to target and fill existing gaps in the relevant literature