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Despite that, for a long time, it was believed that no neurons are made in adult brains, the evidence that neurogenesis is also possible in human adult in the SVZ, in the sub-granular zone (SGZ) on the hippocampal dentate gyrus (DG), and in the olfactory bulb (Zhao and Moore, 2018) strikingly reversed that dogma, opening the possibility to employ stem cells as new tools for therapeutic purposes in neural regeneration/repair in diseases and after injuries (Figure 6)

however, this association became unstable when accounting for confounding factors