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About Wegovy HD (semaglutide) injection 7.2 mg The FDA approval of Wegovy HD is based on the results of the STEP UP program, which included the phase 3 STEP UP clinical trial, which was a 72-week randomized, double-blinded, placebo-controlled and active-controlled superiority trial designed to evaluate the efficacy and safety of once-weekly semaglutide injection 7.2 mg compared to semaglutide injection 2.4 mg and placebo as an adjunct to lifestyle intervention.1,2 1,407 adults with BMI 30 kg/m2 without diabetes were included in the trial

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