After being applied to the skin of psoriatic mice, the Cur-CNE embedded oligopeptide hydrogel (Cur-CNEs/Gel) provided a prolonged residue time of Cur-CNEs on the skin lesion
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For weekly injections (such as semaglutide or tirzepatide), if your scheduled injection day falls during travel: Administer before departure if you're travelling on your usual injection day, ideally at your normal time For any schedule adjustments, consult your medication's patient information leaflet (PIL) or Summary of Product Characteristics (SmPC) for specific guidance on missed doses or changing injection days Speak with your prescribing clinician before departure for personalised advice, especially for long-haul travel across multiple time zones For daily injections (such as liraglutide): Try to administer at approximately the same time each day according to local time If you miss a dose, follow the specific guidance in your medication's PIL Practical management strategies: Set reminders on your phone adjusted for local time zones Identify private, clean spaces for administration (hotel bathrooms, airport family facilities) Carry alcohol swabs and ensure proper hand hygiene before injecting Dispose of sharps safely in your travel sharps containernever in regular waste bins Monitor for adverse effects, which may be exacerbated by travel stress, dehydration, or dietary changes Common side effects of these medications include nausea, vomiting, diarrhoea, and constipation

10.3389/fendo.2021.645617 22 Merck (2017)