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Abbreviations MDA: Malondialdehyde SMR: Summary-data-based mendelian randomization GWAS: Genome-wide association studies GC: Gastric cancer GBA1: Glucocerebrosidase MUC1: Mucin 1 MTX1P1: Metaxin 1 pseudogene SYT11: Synaptotagmin 1 GSH: Glutathione eQTL: Expression quantitative trait loci mQTL: Methylation quantitative trait loci GTEx: Genotype tissue expression SNP: Single nucleotide polymorphisms IVW: Inverse variance weighting LD: Linkage disequilibrium TME: Tumor microenvironment GEO: Gene expression omnibus scRNA: Single-cell RNA ROS: Reactive oxygen species References Smyth EC, Nilsson M, Grabsch HI et al (2020) Gastric cancer