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Description

Seek medical evaluation for persistent or concerning symptoms , especially if itching is accompanied by rash, bleeding, or significant discomfort

Patients will maintain the standard 0.25mg dose for the first four weeks before increasing to 0.5mg in the fifth week, followed by 1mg for the subsequent increase

Statins could reduce the synthesis of cholesterol, thus increasing the number and activity of low-density lipoprotein (LDL) receptors on the membrane of liver cells and enhancing the clearance of plasma cholesterol [1, 2]