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However, conventional oral B12 supplements, such as cyanocobalamin and methylcobalamin, face significant challenges during their transit through the GI tract (23)

The use of GLP-1 drugs may be associated with an increased risk of bowel obstruction due to their mechanism of slowing gastric emptying and altering gut motility

doi: 10.1038/s41598-017-16327-z 160 TruiniAAlamaADal BelloMGCocoSVanniIRijavecEet al

For example, studies have shown that neuron-specific proteins, such as nerve growth factor and BDNF, exhibit significant changes in expression in both the blood and brain tissues of individuals with depression