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This was shown when a group of mice had improved symptoms of Metabolic Syndrome (MetS) including better regulation of glucose, triglycerides, and cholesterol levels after being given IGF-1.: Insulin growth factor 1 (IGF-1) has multiple effects on metabolism

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Unlike endogenous antioxidants, synthetic supplements, such as vitamin C pills, may disrupt redox signaling by non-specifically scavenging ROS, including beneficial low-level oxidants that play a role in metabolic regulation (Mazidi et al., 2020)