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What GLP-1 Medications Are and How They Work GLP-1 receptor agonists mimic a natural hormone that helps control appetite, digestion, and insulin response

To confirm that increases in islet GLP-1 expression correspond with increases in the active form of GLP-1, we measured active GLP-1 in islet protein lysates from islets from a human donor (Supplemental Figure 5B) following 24 hours of treatment with saline or liraglutide