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Additionally, quercetin has demonstrated protective effects against Cis-induced AKI in vivo (Snchez-Gonzlez et al., 2017) and has been shown to safeguard human renal proximal tubular cells against the toxicity of radiocontrast media in vitro (Lu et al., 2018) illustrated that quercetin diminishes kidney injury by modulating the polarization of M1/M2 macrophages, thereby providing evidence that quercetins improvement of kidney inflammation and injury may be linked to macrophage function regulation

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