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The (His) 6 -tag was removed by overnight thrombin cleavage, followed by polishing with size-exclusion chromatography (SEC) using a Superdex 75 HiLoad 16/600 column (Cytiva, MA, USA) equilibrated in 20 mM Tris-HCl pH 8.0, and 150 mM NaCl

Comparison of exosome-mimicking liposomes with conventional liposomes for intracellular delivery of siRNA

By moderately promoting oxidative stress, the antioxidant defense mechanisms of vascular endothelial cells can be activated, reducing the formation of oxidized LDL and thus alleviating the progression of atherosclerosis [197]

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