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Potential Side Effects: Monitoring for Adverse Reactions Monitoring for potential side effects is essential when contemplating the long-term use of GLP-1 medication for weight loss and overall health improvement

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NICE TA664 recommends semaglutide for adults with a BMI of 35 kg/m or above (or 3034.9 kg/m in certain circumstances) alongside at least one weight-related comorbidity, used within a specialist NHS weight management service for a maximum of two years

Supplementary information Glossary B6.NZM2410.Sle1.Sle2.Sle3 triple-congenic mouse model A genetically engineered model on a C57BL/6 background combining three susceptibility loci from Sle, Sle2 and Sle3, leading to spontaneous lupus-like disease