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Research shows NAD+ precursors may protect neurons from oxidative stress, support neurotransmitter production, and improve markers associated with cognitive decline

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Specifically, IGF-I can increase the number of CD4 + CD8 + immature T cells in rat thymus and spleen[162], promotes T cell survival[163], proliferation, chemotaxis and maturation, and blocks spontaneous and induced programmed cell death[163, 164], although it has also been reported to block IL-2-dependent lymphocyte growth and function[165]

Fresh is better than frozen, especially with cruciferous vegetables [28]