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Delta-sleep inducing peptide (DSIP) and ACTH (4-10) analogue influence fos-induction in the limbic structures of the rat brain under emotional stress

Research has examined glutathione and its precursor N-acetyl cysteine (NAC) and found clinical benefit in treating peripheral artery disease 2 , Parkinsons disease 3 , fatty liver 4 , coronary reperfusion injury 5 , bipolar disorder 6-7 obsessive compulsive disorder 8 , schizophrenia 6,9,10 , addiction treatment 11-12 , autism 13 and flu prevention 14

The rationale for combining them is mechanistic complementarity (different signaling pathways, all three implicated in tissue repair and dermal remodeling) and clinical anecdote in the peptide-therapy community not formal head-to-head, combination-vs-monotherapy, or concentration-response data on the blend itself

Both lack human trials