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Creatine can be obtained through the diet at about 1g/day from non-vegetarian sources (concentration of creatine in meat and fish range between 4 and 5g/Kg) As creatine is predominately present in non-vegetarian sources, vegetarians and vegans have lower resting creatine concentration

Immune checkpoint inhibitors (ICIs), a novel class of antineoplastic remedies, have shown clinical efficacy toward a variety of intractable tumors

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