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Its dysregulation is linked to diseases such as iron-deficiency anemia and hereditary hemochromatosis [9, 10]

the subject in need of treatment using methods as described herein may be a subject having impairment in one or more behavioural traits which are assessed by one or more of: a responder as described herein may be defined as a subject with an abnormal score on one or more of the behavioural assessments above

Under conditions of abnormal microbiota homeostasis, for example where high fat diets contribute to obesity, circulating levels of 2MBC are elevated