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Diabetes Care 38 , 12631273 (2015)

While intensive glycemic treatment to achieve low HbA1c targets reduced the long-term risk of microvascular complications (retinopathy, nephropathy, and peripheral neuropathy), it has not been shown to significantly reduce the risk of major adverse CV events [24-27]

Likewise, the increase in markers of FAO and ketogenesis in the liver, as well as blood ketone bodies, were not observed in mice co-treated with ATGLi (Fig